Hepatology/Liver

Y-90 Radioembolization Dosimetry Calculator

Free Y-90 Radiation Segmentectomy Calculator. Calculate activity dose for yttrium-90 radioembolization using MIRD and partition models. LSF and lung dose safety limits.

References

  1. Ho S et al. Partition model for estimating radiation doses from Y-90 microspheres in treating hepatic tumours. Eur J Nucl Med. 1996
  2. Lewandowski RJ et al. Radiation segmentectomy: a novel approach for liver tumor treatment. J Vasc Interv Radiol. 2015
  3. Salem R et al. Radioembolization for hepatocellular carcinoma using Yttrium-90 microspheres: a comprehensive report. Cancer. 2010
  4. Kennedy A et al. Recommendations for radioembolization of hepatic malignancies using Y-90 resin microspheres. Int J Radiat Oncol Biol Phys. 2007
  5. Riaz A et al. Radiation segmentectomy: a novel approach to increase safety and efficacy. Int J Radiat Oncol Biol Phys. 2011
  6. Garin E et al. Personalised versus standard dosimetry approach of selective internal radiation therapy in HCC. Lancet Oncol. 2021
  7. Chiesa C et al. EANM dosimetry committee guidance document: radioembolisation. Eur J Nucl Med Mol Imaging. 2021
  8. Pasciak AS et al. The number of microspheres in Y-90 radioembolization. J Nucl Med. 2016
  9. Strigari L et al. Efficacy and toxicity related to treatment of hepatocellular carcinoma with Y-90. J Nucl Med. 2010
  10. Kao YH et al. Post-radioembolization yttrium-90 PET/CT - part 1: diagnostic reporting. EJNMMI Res. 2013
  11. Vouche M et al. Unresectable solitary HCC: long-term toxicity and outcomes after radiation segmentectomy. Radiology. 2015
  12. Chow PKH et al. SIRveNIB: Selective Internal Radiation Therapy Versus Sorafenib. J Clin Oncol. 2018
  13. Vilgrain V et al. Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres. Lancet Oncol. 2017
  14. AAPM Task Group Report: Guidance for Y-90 radioembolization dosimetry and treatment planning
  15. TheraSphere Y-90 Glass Microspheres Package Insert - Boston Scientific