Interventional

Inferior Petrosal Sinus Sampling (IPSS) Calculator

Free IPSS Calculator for Cushing's disease. Inferior Petrosal Sinus Sampling with CRH stimulation, ACTH/prolactin ratios, and lateralization for pituitary vs ectopic ACTH.

References

  1. Oldfield EH et al. Petrosal sinus sampling with and without CRH for differential diagnosis of Cushing's syndrome. N Engl J Med. 1991;325(13):897-905.
  2. Lefournier V et al. Accuracy of bilateral inferior petrosal or cavernous sinuses sampling in predicting the lateralization of Cushing's disease pituitary microadenoma. J Clin Endocrinol Metab. 2003;88(1):196-203.
  3. Colao A et al. Inferior petrosal sinus sampling in the differential diagnosis of Cushing's syndrome: results of an Italian multicenter study. Eur J Endocrinol. 2001;144(5):499-507.
  4. Nieman LK et al. The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2008;93(5):1526-1540.
  5. Wind JJ et al. The lateralization accuracy of inferior petrosal sinus sampling in 501 patients with Cushing's disease. J Clin Endocrinol Metab. 2013;98(6):2285-2293.
  6. Machado MC et al. The inferior petrosal sinus sampling with/without desmopressin: enhancement with prolactin-to-ACTH gradient. Eur J Endocrinol. 2007;157(1):29-39.

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